Lyon,
France, October 8-10 2004
program
Lyon,
France, October 8-10 2004 |
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program |
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PROGRAM |
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| FRIDAY
- October 8 |
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| 12:00 - 14:00 | Welcome, Registration and Poster setup | Atrium |
| 14:00 | Meeting Introduction | Amphitheatre Charles Merieux |
Session
I - Commensal Bacteria in Mucosal Immunity Chair : Nadine Cerf-Bensussan & Per Brandtzaeg |
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| 14:30 - 16:00 | Plenary Session I | Amphitheatre Charles
Merieux |
| 14:30 - 15:00 | Andrew
J MacPherson (Institute for Experimental Immunology, Zurich,
Switzerland) Innate IgA production against commensal bacteria |
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| 15:00 - 15:30 | Dana Philpott
(Institut Pasteur, Paris, France) TLRs and Nod2 as sensors of Bacteria |
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| 15:30 - 16:00 | Pierre Desreumaux
(Inserm U114, Lille, France) Probiotics and PPAR-gamma in the treatment of Intestinal Inflammatory Diseases |
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| 16:00 - 16:30 | Coffee break | Atrium |
| 16:30 - 18:00 | Selected oral presentations from Posters | Amphitheatre Charles Merieux |
| Session I - Commensal bacteria in Mucosal Immunity | ||
| I-1 |
Jean-Christophe
Bambou (Inserm EMI-0212, Paris, France) Proinflammatory role of commensal enteric bacteria in vitro and in vivo: example of Escherichia coli |
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| I-9 |
Catherine Daniel
(Institut Pasteur de Lille, Lille, France) Recombinant lactic acid bacteria: a novel vaccination strategy against type I birch pollen allergy |
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| I-6 |
Monica Carol
(University Hospital Vall d’Hebron, Barcelona, Spain) Lactobacillus casei can overcome resistance to apoptosis in lymphocytes from patients with Crohn’s disease |
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| I-20 |
Jan Zizka (Charles University,
Prague, Czech Republic) Evolution of cytokine levels in the first year of life of children of allergic and non-allergic mothers |
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| Session VI - other topics | ||
| VI-2 |
Matthieu Allez (Inserm
U396, Paris, France) Activation of CD4+ effector T cells through MICA-NKG2D epithelial interactions in Crohn’s disease |
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| VI-12 |
Annemarie Hasselberg
(Göteborg University, Göteborg, Sweden) Induction of T cell tolerance via antigen targeting to B cells |
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| 18:00 - 22:00 | Poster viewing and Buffet dinner | Atrium |
| SATURDAY
- October 9 |
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Session
II - Dendritic cells in Infection, Inflammation and Tolerance Chair : Maria Rescigno & Pat Holt |
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| 9:00 - 10:30 | Plenary Session II | Amphitheatre Charles
Merieux |
| 9:00 - 9:30 | Allan McI Mowat (University
of Glasgow, Glasgow, Scotland) Dendritic Cells in Immunity and Tolerance to Orally Administered Antigens |
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| 9:30 - 10:00 | Pat Holt (Telethon
Institute for Child Health Research, Perth, Australia) Regulation of T cell activation in the Airway Mucosa by resident Dendritic Cells |
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| 10:00 - 10:30 | Paola Ricciardi-Castagnoli
(University of Milano-Bicocca, Milan, Italy) Interpretation of the Plasticity of Dendritic Cells by Functional Genomics |
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| 10:00 - 11:00 | Coffee break | Atrium |
| 11:00 - 12:00 | Selected oral presentations from Posters | Amphitheatre Charles Merieux |
| II-5 |
Alexandra
Eberhard (Weizmann Institute, Rehovot, Israel) In vivo imaging of pathogen uptake by lamina propria dendritic cells |
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| II-7 |
Anne Goubier (INSERM
U404, Lyon, France) Liver plasmacytoid dendritic cells contribute to oral tolerance |
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| II-19 |
Malin Sundquist
(University of Göteborg, Göteborg, Sweden) Mechanism of in vivo dendritic cell maturation in response to oral Salmonella infection |
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| II-2 |
Fabienne Anjuère
(INSERM E215, Nice, France) In vivo adjuvant-induced mobilization and maturation of gut dendritic cells after oral administration of Cholera Toxin |
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| 12:00 - 14:00 | Buffet lunch and Poster Viewing | Atrium |
Session
III - Regulatory T cells in Mucosal Inflammation Chair : Fiona Powrie & Rainer Duchmann |
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| 14:00 - 15:30 | Plenary Session III | Amphitheatre Charles
Merieux |
| 14:00 - 14:30 | Fiona
Powrie (School
of Pathology, Oxford, United Kingdom) Therapeutic potential of CD4+CD25+TR in Chronic Intestinal Inflammation |
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14:30 -
15:00 |
Hervé Groux
(INSERM U343, Nice, France) Dendritic cell Cross-talk with Regulatory CD4+ T cells |
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| 15:00 - 15:30 | Bertrand Dubois
(INSERM U404, Lyon, France) Regulatory CD4+CD25+ T cells in oral tolerance |
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| 15:30 - 16:00 | Coffee break | Atrium |
| 16:00 - 17:00 | Selected oral presentations from Posters | Amphitheatre Charles Merieux |
| III-2 |
Per Brandtzaeg (Institute
of Pathology, Oslo, Norway) Allergen-responsive CD4+CD25+ regulatory T cells in children who have out-grown cow’s milk allergy |
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| III-12 |
Dominique Buzoni-Gatel (Institut
Pasteur, Paris, France) NKT cells play a crucial role in the initiation of the inflammatory intestinal process after infection with Toxoplasma gondii |
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| III-14 |
Alexander Scheffold
(Deutsches Rheuma-Forschungzentrum, Berlin, Germany) IL-2 induces IL-10 production in CD4+CD25+ Tregs |
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| III-9 |
Edward Lavelle (Trinity
College, Dublin, Ireland) Selective modulation of dendritic cell activation and induction of antigen-specific regulatory T cells by bacterial toxins |
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| 17:00 | End of session | |
| 20:00 |
Gala Dinner & Party |
“L’EMBARCADERE" |
address : 13 Quai Rambaud, 69002 Metro PERRACHE Bus #8, stop "Claudius Collonges" 500 meter from the TGV train station "Perrache" |
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| SUNDAY
October 10 |
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Session
IV - Novel Routes and Adjuvants for Mucosal Vaccines Chair : Jan Holmgren & Marc Girard |
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| 9:00 - 10:30 | Plenary Session IV |
Amphitheatre Charles
Merieux |
| 9:00 - 9:30 | Jan Holmgren (GUVAX,
University of Göteborg, Göteborg, Sweden) Mucosal Adjuvants and Anti-Infection and Anti-Immunopathology Vaccines based on Cholera Toxin, Cholera Toxin B subunit and CpG DNA |
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| 9:30 - 10:00 | Cecil Czerkinsky (INSERM
E215, Nice, France) Transepithelial Immunomodulation and Vaccine Development |
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| 10:00 - 10:30 | Ali Harandi (GUVAX,
University of Göteborg, Göteborg, Sweden) CpG DNA linked to CTB: a novel, extremely potent Immunostimulatory Adjuvant |
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| 10:30 - 11:00 | Coffee break | Atrium |
| 11:00 - 12:00 | Selected oral presentations from Posters | Amphitheatre Charles Merieux |
| IV-17 |
Jean-Claude Sirard (Institut
de Biologie de Lille, Lille, France) Adjuvant properties of the Toll-like Receptor 5 agonist, bacterial flagellin, by the mucosal route |
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| IV-16 |
Marianne Quiding-Järbrink
(University of Göteborg, Göteborg, Sweden) Human antibody-secreting cells induced by mucosal, but not systemic, immunization respond to TECK (CCL25) and MEC (CCL28) |
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| IV-6 |
Nathalie Etchart (INSERM
U404, Lyon, France) Measles virus nucleoprotein (NP) is a selective adjuvant of cross-primed CD8+ T cell responses after mucosal immunisation |
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| IV-15 |
Johanna Nystrom (GUVAX,
University of Göteborg, Göteborg, Sweden) Protection against Helicobacter pylori infection in mice after therapeutic immunization is related to mucosal specific antibody and CD4+ T cell responses |
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| 12:00 - 13:30 | Break and Poster Viewing |
Atrium |
Session
V - Mucosal Immunity against HIV Infection and Vaccination Strategies (Session sponsored by ANRS) Chair : Anne Hosmalin & Kenneth Rosenthal |
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| 13:30 - 13:40 | Introduction by Anne Hosmalin | Amphitheatre Charles
Merieux |
| 13:40 - 15:10 | Plenary Session | |
| 13:40 - 14:10 | Juliana McElrath
(University of Washington, Seattle, USA) HIV infection and T cell responses in the Genital Tract |
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| 14:10 - 14:40 | Kristina Broliden
(Karolinska Institutet, Stockholm, Sweden) Function and Specificity of the Mucosal Immune Response in HIV-exposed uninfected individuals |
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| 14:40 - 15:10 | Morgane Bomsel
(Institut Cochin, Paris, France) Characterisation of HIV neutralizing IgA by screening a phage-display Fab IgA library derived from Mucosal HIV Highly Exposed but IgG Sero-Negative Individuals |
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| 15:10 - 16:00 | Selected oral presentations from Posters | Amphitheatre Charles
Merieux |
| V-6 |
Lucia Lopalco
(San Raffaele Scientific Institute, Milan, Italy) CCR5-infection-protecting mucosal IgA in Long Term Non Progressors HIV infected and in HIV-Exposed but Uninfected individuals |
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| V-7 |
Carmelo Luci (INSERM
E215, Nice, France) Induction of IFN-g producing specific CD8+ T cells after intravaginal immunization with an heterologous antigen coupled to the B subunit of Cholera toxin |
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| V-8 |
Karine Petitprez
(Hopital Cochin, Paris, France) Reproducible measures of levels and functional activities of antibodies against HIV gp160 in cervicovaginal, rectal, nasal, and oral compartments in HIV-1 infected women : National French Agency for AIDS Research (ANRS) pre-VAC14 trial |
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| 16:00 - 16:30 | Coffee break | Atrium |
| 16:30 - 17:30 | Plenary Session | Amphitheatre Charles
Merieux |
| 16:30 - 17:00 | Kenneth Rosenthal
(McMaster University, Hamilton, Ontario) Novel Mucosal Adjuvants and Anti-Infectives: The Toll Route |
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| 17:00 - 17:30 | Robin Shattock
(St George’s Hospital Medical School, London, United Kingdom) Sexual Transmission of HIV: from Mechanisms to Microbicides |
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| 17:30 - 18:00 | Selected oral communications from Posters | Amphitheatre Charles Merieux |
V-5 |
Philip
Lawrence (Faculté de Médecine J. Lisfranc,
St Etienne, France) Construction and tropism characterization of infectious recombinant viruses exhibiting HIV-1-env from seminal strains |
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| V-1 |
Marielle Bouschbacher (Université
Claude Bernard, Lyon, France) Mechanisms of HIV entry and dissemination in pluristratified human mucosa : exploration of a 3D reconstructed vaginal mucosal model |
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| 18:00 | End of Meeting | |